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What if lung cancer metastasized to the adrenal glands?

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What if lung cancer metastasized to the adrenal glands?

QuestionsCategory: cancerWhat if lung cancer metastasized to the adrenal glands?
Mukthi asked 6 months ago
What if lung cancer metastasized to the adrenal glands?

1 Answers
Dr. Bommu Venkateshwara Reddy Staff answered 6 months ago
Adrenal gland metastasis is an indication of an advanced stage of lung cancer spread. When lung cancer cells move to these glands and form new tumors, it may lead to many symptoms as the adrenal glands are crucial hormone-producing organs located above the kidneys.  

Understanding Metastasis:

  How Does It Happen?
  • The cancer cells dissociate from the primary tumor on the lung.
  • They proceed via the bloodstream and the lymphatic system to the adrenal gland.
  • These cells divide rapidly to give rise to new tumors on the adrenal glands.
  Why Target the Adrenal Glands?
  • The affinity of cancer cells for specific areas like the adrenal glands remains partially unexplained.
  • Scientists believe it might relate to the adrenal glands' blood vessel network or internal environment that may promote cancer growth.
 

The Primary Causes

  Lung cancer is additionally inclined than multihued distinct malicious tumors to grow into adrenal metastases, specifically stomach, esophageal, and liver tumors. Cancers that multiply to the adrenal glands consist of kidney cancer, carcinoma, bone cancer, colon cancer, and lymphoma.  

Prevalence and Early Detection

  Adrenal metastasis commonly occurs in lung cancer, affecting about 2% to 3% of patients at their initial diagnosis. Sometimes, adrenal metastasis is the first indication of lung cancer.  

Staging and Prognosis

  Once lung cancer reaches the adrenal glands, doctors classify it as stage 4, a more advanced disease state. The prognosis for adrenal metastasis greatly depends on its location relative to the primary tumour. Ipsilateral metastasis (on the same side as the original lung tumour) usually has a better outlook compared to contralateral spread (to the opposite side) or to other areas.  

Symptoms and Discovery

  Most people with adrenal metastases show no symptoms. Only around 5% of affected individuals experience symptoms such as back pain, abdominal pain, internal bleeding, and Addison's disease indicators like weakness, low blood pressure, and blood sugar and electrolyte imbalances. Doctors often find these metastases incidentally during lung cancer radiological studies.  

Survival Rates and Treatment Innovations

  Patients' median survival with adrenal metastases depends on the cancer type and metastasis extent. Recent studies have shown promising results with aggressive surgical treatment of adrenal metastases. A 2011 study reported an 83% five-year survival rate for patients with surgery for both primary lung cancer and ipsilateral adrenal metastasis. However, patients with contralateral metastasis had a drastically lower five-year survival rate.  

Final Thoughts

  Every cancer journey is unique. The most effective approach includes a team of healthcare professionals, personalized treatment plans, and support for physical and emotional needs. Stay informed and hopeful, and always feel free to ask questions or seek second opinions. Your healthcare journey is yours, with your team supporting you every step of the way.

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