Non-Hodgkin lymphoma cancer

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1. About the Lymphatic System:

Thin tubes and clusters of tiny, bean-shaped organs called lymph nodes. These nodes are distributed throughout the body, constituting the lymphatic system in our body. The chest, underarms, groin, pelvis, belly, and neck all have dense collections of lymph nodes.

Lymphocytes (white blood cells) are in the colorless fluid known as lymph. These are carried through the lymphatic system. Lymphocytes in the immune system assist the body to battle against pathogens. Several lymphocyte types include:

B cells: These are also known as B lymphocytes. They produce antibodies that fight germs and other ailments.

T lymphocytes: Generally called T cells. These cells kill viruses and foreign cells and direct the production of antibodies by the B cells.

Natural killer (NK) cells: NK cells eliminate intruders that include viruses, virus-infected cells, and some cancer cells

01_Lymphoma Cancer

Lymphoma – Non-Hodgkin:

Lymphoma is the lymphatic system in the body. Healthy B cells, T cells, or NK cells in the lymphatic system alter and increase uncontrollably in number to the point that they can develop into Lymphomas/tumors. And the specific type of Lymphoma is called Hodgkin Lymphoma. NHL is the name for a class of lymphatic system malignancies. In contemporary medicine, different symptoms, physical examinations, and therapies can be associated with these cancers.

2. Where does Non-Hodgkin Lymphoma Cancer develop?

As was previously mentioned, the immune system includes the lymph system that aids in the fight against infections and several other disorders. It also facilitates the movement of bodily fluids.

Lymphomas can develop anywhere in the body that has lymph tissue. The lymphoid tissue can be found in the following:

  • Lymph nodes: We can find lymph nodes inside the chest, abdomen, and pelvis. These are bean-sized clusters of lymphocytes and other immune system cells. A network of lymphatic vessels links them.
  • Spleen: It is located on the left side of the body, under the lower ribs. The spleen produces lymphocytes and some other immune system cells. Moreover, it preserves healthy blood cells by pushing out bacteria, cell waste, and damaged blood cells.
  • Bone marrow: It is the spongy tissue found inside significant bones, and it is the bone marrow. Here, some lymphocytes and new blood cells are produced.
  • Thymus: It is a little organ located in front of the heart, behind the upper portion of the breastbone is called the thymus. It is important in the growth of T lymphocytes.
  • Adenoids and tonsils: You can find these lymph tissue clusters in the back of the throat. They work for the production of antibodies that protect against ingested or inhaled pathogens.
  • Digestive tract: With all the above, the stomach, intestines, and many organs have lymph tissues.

3. Types of Non-Hodgkin Lymphoma:


02_Types of Lymphoma Cancer

The lymphatic system is a body component that includes the immune system. Non-Hodgkin Lymphoma (NHL), a particular type of cancer, emerges there. It is found through research that there are numerous forms of NH. They can be divided into distinct groups based on characteristics. Doctors interpret these as the particular lymphocyte type afflicted, the look of the cancer cells, and how the disease behaves. 

Following are a few of the common non-Hodgkin Lymphoma varieties:

Diffuse Large B-Cell Lymphoma (DLBCL): 

Today, this is the most prevalent form. It could appear anywhere in organs, lymph nodes, or other tissues and can expand quickly. About 30% of NHL cases fall within this category.

Follicular Lymphoma: 

Follicular cells, an aberrant B-lymphocyte subtype, can distinguish this kind of NHL from others. As per the studies, it frequently appears in the lymph nodes, bone marrow, and spleen. Generally, this cancer develops slowly.

Mantle Cell Lymphoma: 

It is an aggressive NHL that develops from B-lymphocytes in the mantle zone of the lymph nodes. This tumor is relatively uncommon but can spread and grow swiftly.

Burkitt Lymphoma: 

Burkitt Lymphoma is an aggressive variant of NHL frequently found in children and young people. It is probably located in the jaw, cheek, belly, or ovaries and is connected to abnormal B-cells.

Marginal Zone Lymphoma: 

To make it easy to understand, lymph nodes, spleen, or other organs are just a few locations where marginal zone Lymphoma can develop in the body. Abnormal B-cells distinguish it in the marginal zone of the lymphoid tissue.

T-Cell Lymphomas: 

T-cell Lymphomas, in contrast to the majority of NHLs, develop from abnormal T-lymphocytes. So, peripheral T-cell Lymphoma and anaplastic large-cell Lymphoma are two examples of T-cell Lymphomas.

Cutaneous Lymphomas: 

These NHLs primarily affect the skin. Its forms are Sézary syndrome and mycosis fungoides.


4. Risk Factors that Cause Non-Hodgkin’s Lymphoma:

As Non-Hodgkin’s Lymphoma is complex and Multifunctional, several factors have been identified that may contribute to these tumors. At the same time, please note that having one or more risk factors does not imply that a person would undoubtedly be at risk for NHL. For your information, below is a comprehensive list of some common risk factors associated with the NHL.

  • Age: NHL is more prevalent in older people. This risk begins to rise sharply around age 60.
  • Weakened immune system: Individuals can have weakened immune systems for many reasons. For example, people with HIV/AIDS or those who have undergone organ transplantation and are taking immunosuppressive medications can be considered. These people are prone to develop the NHL problem.
  • Infections: 

Viral and bacterial infections like;

  • Epstein-Barr virus (EBV)
  • Hepatitis C virus (HCV)
  • Human T-cell leukemia (HTLV-1)
  • Human herpesvirus-8 (HHV-8) and Helicobacter pylori infection can quickly increase the risk of NHL.
  • Genetic factors: An increased likelihood of developing NHL is associated with genetic illnesses, including inherited immunological disorders. 
  • Family history: A first-degree family with NHL, like a parent or sibling, can make one prone to NHL.
  • Chemical exposures: Exposure to certain chemicals and toxins, like pesticides, some solvents, and herbicides, can create this condition. 
  • Autoimmune diseases: If an individual has certain autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus, and Sjögren’s syndrome, they have a slightly higher risk of NHL.
  • Obesity: Particularly in women, obesity can be an increased risk of NHL.


6. Signs and Symptoms of Non-Hodgkin Lymphoma Cancer:

A person who suffers from the following signs or symptoms could be affected by non-Hodgkin Lymphoma (NHL). NHL is very complex and has a variety of other, less dangerous diseases in common with its signs and symptoms. It is typically referred to as a hematologist-oncologist.

It is important to remember that lymph nodes swelling in the body painlessly is the most typical early symptom of NHL. So, one can find such protruding neck, armpit, or groin regions in most NHL patients.

A comparatively less frequent case is that a swollen node develops in the throat close to the tonsils, near the ears, or at the elbow. In these situations, patients may have symptoms connected to that particular spot. Likewise, a bone, a lung, the digestive tract, or part of the skin can be some examples of places other than the lymph nodes. And note that the NHL occasionally begins here.

04_Signs And Symptoms Of Lymphoma Cancer

Below is the list of symptoms of NHL;

  • Without any pain, you can find an enlargement in one or more lymph nodes
  • A sudden and unexplained fever
  • moist night sweats
  • persistent fatigue for no reason
  • reduced appetite
  • Unaccounted weight loss
  • Pain in the chest or a cough
  • feeling heavy and full due to an enlarged spleen
  • Skin itch
  • Feeling the expansion of the liver or spleen
  • Skin rashes or lumps

As some people have no symptoms, the disease might only be discovered once the patient has undergone a standard checkup, probably while receiving treatment for another ailment.

B Symptoms of NHL:

Fever, intense night sweats, and a weight loss condition of around 10% over months are “B symptoms.” While diagnosing, B symptoms are essential for disease stage and prognosis. Itching and weariness are two additional NHL symptoms not categorized as B symptoms.

6. Stages in the growth of Non-Hodgkin’s Lymphoma:

The Lymphoma stage indicates how widely the tumor has spread in the body. The prevalent subtypes of Lymphoma can benefit from the staging system. If the tumor is discovered in other subtypes, it is evident that the tumor is already spread to every part of the body. The prognostic factors take on additional significance in such circumstances. Hence, it’s crucial to remember that even stage IV Lymphomas can be successfully treated.

Stage I: 

Carefully observe whether one of these conditions applies:

One area of a lymph node has cancer. Or, the tumor has invaded one extra lymphatic organ or site but not the lymph node regions, and this is stage IE.

Stage II: 

Carefully observe whether one of these conditions applies:

Suppose the tumor has spread to 2 or more lymph node locations on one side of the diaphragm – then it is stage II. or, with or without cancer in other lymph node sections on one side of the diaphragm, cancer affects any one organ, and its regional lymph nodes can be named stage IIE.

Stage III-IV: 

Stage III NHL is present in the lymph nodes on either side of the diaphragm. If it has moved outside the lymph nodes to other body parts, then it must be stage IV. It is essential to have information that the liver, bone marrow, and lungs are where Lymphoma spreads very quickly. 

Also, stage III and IV Lymphomas are prevalent depending on the NHL subtype. Stages III and IV are grouped here because they receive the same care and prognosis. Of course, they are generally curable.


It could be a problem when cancer spreads while the patient receives treatment for the initial Lymphoma. This condition is also known as NHL refractory.

Subcategories A and B: 

An (absence of symptoms) or B (presence of symptoms) is added after the stage to indicate whether any symptoms are present. Many such symptoms are understood from many cases, like unexplained weight loss, fever, or night sweats. 

Stage IIIB, for instance, denotes NHL with symptoms that affect the lymph node regions on either side of the diaphragm.

Recurrence of Lymphoma:

If the illness recurs after therapy, we call this recurrent Lymphoma. Because it might return to the same spot where it started. Recurrence can be expected immediately following the initial therapy or a few years later. If the tumor recurs, it needs to be staged again using the above mentioned approach. NHL relapse is another name for this.

7. Prevention of Non-Hodgkin Lymphoma Cancer:

06_Prevention Of Lymphoma Cancer copy

The NHL cannot be prevented. Still, there are ways where one can stay away from well-known risk factors, including obesity and HIV. Following the prevention below can help you reduce your risk for this condition:

  1. Remember to use barrier methods each time you engage in sexual activity, which can lower your chances of contracting HIV. 
  2. Avoid intravenous drug use or using clean needles when injecting drugs can save you from contracting HIV/ hepatitis C. 
  3. The below list can help prevent obesity and may protect against Lymphoma: 
  • Maintain a healthy weight. 
  • Always workout and be physically active 
  • Follow a nutritious diet with fruits, veggies, and whole grains. Along with that, limit sugary drinks, red or processed meats, and processed foods. 
  1. At the same time, parameters like age and family history are two significant risk variables that cannot be controlled.

How Punarjan Ayurveda Treats Non-Hodgkin’s Lymphoma?

Punarjan Ayurveda employs a complete approach for those with Non-Lymphoma Hodgkin’s today that goes above and beyond conventional medical care. Each patient receives a tailored treatment plan from one of our highly skilled ayurvedic practitioners. We work to repair the physical body and spiritual life with the aid of herbal medications and conscious lifestyle adjustments. We begin each person’s recovery by carefully examining their tridosha constitution. Ayurveda medicines can boost immunity, promote overall health, and decrease the adverse effects of other treatments.

Our guiding principle is synergy. Bhasmas are created using naturally occurring metals and a variety of organic botanicals. Some medications have immunomodulatory and natural detoxifying effects. There is a path to recovery from Non-Lymphoma Hodgkin’s through Punarjan Ayurveda. We created an ecosystem that encourages positivity, sturdiness, and adaptability together.

Punarjan believes that ayurvedic cancer treatment is based on respect for life and a solid belief in the natural ability of our bodies to heal. At the intersection of science and soul, we are ready to assist you. We want to make it possible for people to relish memorable occasions and embark on a secure path to better health and energy.

Our Lymphoma Cancer Survivor Stories


Is non-Hodgkin’s lymphoma a cancer?

This type of cancer strikes the body’s defense system – specifically non-Hodgkin’s lymphoma. Abnormal expansion of white blood cells signifies this disease. In terms of frequency, Non-Hodgkin’s lymphoma exceeds Hodgkin’s lymphoma.

Is non-Hodgkin’s lymphoma serious?

Yes, This malignancy begins in the body’s immune network, particularly the lymphatic system. Lymphoma’s severity changes greatly depending on the type, diagnosis stage, and patient health. Some cancer varieties can gradually expand, causing minimal problems, whereas others can progress swiftly and necessitate more thorough treatment.

Is non-Hodgkin’s lymphoma cancer curable?

The treatment approach and the patient’s overall condition affect the survival chances of Non-Hodgkin lymphoma in India. Intensive programs offer hope for approximately 30% of patients with advanced stages of the condition. Aggressive manifestations may be unresponsive to treatment.

What is the survival rate for Non-Hodgkin lymphoma?

The treatment approach and the patient’s overall condition affect the survival chances of Non-Hodgkin lymphoma in India. The type of therapy utilized and the patient Investigations reveal an average survival period of 4.2 years following HSCT. Moreover, a novel therapy, Varnimcabtagene autoleucel (IMN-003A), has demonstrated encouraging outcomes with a combined response rate of 71.4% after 90 days.

Is stage 4 lymphoma curable?

Though challenging, treatment options exist for stage 4 lymphoma, enabling potential remission. Due to individual differences, the ultimate result may fluctuate according to numerous variables. Personalized medical counsel should be sought from healthcare experts.

Do people recover from non-Hodgkin’s lymphoma?

Intriguingly, a scarce handful defeat non-Hodgkin’s lymphoma, conquering it whole. Roughly 60% to 85% of this ailment’s patients encounter an assorted chance of enduring beyond five years.

What causes death in non-Hodgkin’s lymphoma?

The disease’s latent consequences can result in fatality. Organ damage caused by cancer treatment can lead to elevated death rates. Multi-organ failure and eventual death can occur as cancer advances and spreads.

Data on Fatality Rates for Hodgkin’s Disease?

As per 2002 statistics, the US witnesses approximately 13.6 deaths due to lymphomas (including non-Hodgkin’s lymphoma) per 100,000 people annually. International rates vary, with San Marino at 30.1 and Norway at 15.2.

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